In this discussion, you will explore how DNA information is turned into specific proteins. What is transcription and translation? What are the different types of mutations? In our next discussion we will look at how these mutations, when occurring in specific genes, can lead to cancer.
For your initial post, compete all of the following:
Describe the basics of transcription and translation. Where in human cells does each of these processes occur?
What are start and stop codons?
What are insertion, deletion, and substitution mutations?
What are frameshift, missense, nonsense, and silent mutations?
Which type of mutation is most likely to cause a change in a protein’s structure and function (frameshift, missense, nonsense, and or silent mutations)? What is least likely to change the protein’s structure and function? Explain.
Write your own sequence of DNA that could be turned into a protein. This should be approximately 30 letters long (10 codons). It should be in the format 3′ AAG CCC ….. 5′
Be sure to include a start codon of “TAC” and a stop codon of your choice. Do not do any transcribing or translating at this time. Just include the DNA sequence in the 3′ to 5′ direction.
Write a mutated sequence based on your first sequence above with either an insertion, deletion, or substitution mutations. Do not write anywhere what type of mutation has occurred. Just write the sequence itself.
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